Molecule Details
| InChIKey | WHUUTDBJXJRKMK-GSVOUGTGSA-N |
|---|---|
| Compound Name | D-Glutamic Acid |
| Canonical SMILES | N[C@H](CCC(=O)O)C(=O)O |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.09 |
| Source | BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB02517 |
|---|---|
| Drug Name | D-Glutamic Acid |
| CAS Number | 6893-26-1 |
| Groups | experimental |
| ATC Codes | nan |
| Description | Glutamic acid is the most common excitatory neurotransmitter in the central nervous system. |
Cross-references: BindingDB: 50002371 ChEBI: 15966 CHEMBL76232 ChemSpider: 21814 Guide to Pharmacology: 1369 IUPHAR: 1369 C00217 PDB: DGL PubChem:23327 PubChem:46508281 RxCUI: 1428878 ZINC: ZINC000000895124
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P39086 | GRIK1 | Homo sapiens | Human | PF01094 PF00060 PF10613 | 6.2 | Ki | BindingDB |
| Q16478 | GRIK5 | Homo sapiens | Human | PF01094 PF00060 PF10613 | 6.1 | Ki | BindingDB |
| Q13003 | GRIK3 | Homo sapiens | Human | PF01094 PF00060 PF10613 | 6.1 | Ki | BindingDB |
| P48058 | GRIA4 | Homo sapiens | Human | PF01094 PF00060 PF10613 | 6.1 | Ki | BindingDB |
| P42262 | GRIA2 | Homo sapiens | Human | PF01094 PF00060 PF10613 | 6.0 | Ki | BindingDB |
DrugBank Target Actions (1)
| Target | Gene | Target Name | Action | Type |
|---|---|---|---|---|
| P43133 | P43133 | Thermolysin | binder | targets |