Molecule Details
| InChIKey | WHTVZRBIWZFKQO-CQSZACIVSA-N |
|---|---|
| Compound Name | (-)-Chloroquine |
| Canonical SMILES | CCN(CC)CCC[C@@H](C)Nc1ccnc2cc(Cl)ccc12 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.45 |
| Source | BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q99720 | SIGMAR1 | Homo sapiens | Human | PF04622 | 7.1 | Ki | BindingDB |
| Q5BJF2 | TMEM97 | Homo sapiens | Human | PF05241 | 6.3 | Ki | BindingDB |
| Q76353 | Human immunodeficiency virus type 1 | Pathogen | PF00552 PF02022 PF00665 | 9.6 | IC50 | BindingDB | |
| P0DTC2 | S | Severe acute respiratory syndrome coronavirus 2 | Pathogen | PF16451 PF09408 PF19209 PF01601 | 6.8 | IC50 | BindingDB |