N-[4-[4-amino-3-(methylcarbamoyl)phenoxy]phenyl]-4-chloro-3-(trifluoromethyl)benzamide

InChIKey	`WHMDUJXKQMEJCM-UHFFFAOYSA-N`
Compound Name	N-[4-[4-amino-3-(methylcarbamoyl)phenoxy]phenyl]-4-chloro-3-(trifluoromethyl)benzamide
Canonical SMILES	`CNC(=O)c1cc(Oc2ccc(NC(=O)c3ccc(Cl)c(C(F)(F)F)c3)cc2)ccc1N`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	6.97
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P15056	BRAF	Homo sapiens	Human	PF00130 PF07714 PF02196	7.1	IC50	ChEMBL;BindingDB
P04049	RAF1	Homo sapiens	Human	PF00130 PF07714 PF02196	7.0	IC50	ChEMBL;BindingDB
P10398	ARAF	Homo sapiens	Human	PF00130 PF07714 PF02196	6.7	IC50	ChEMBL;BindingDB