Molecule Details
InChIKeyWGYPAJVJMXQXTR-ABNZCKJZSA-N
Canonical SMILESC[C@@H]1CN[C@@H](C2CC2)C(=O)N(C)[C@H](C)C(=O)N[C@H](Cc2ccc(F)cc2)C(=O)NCCCc2ccccc2O1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Cross-Family
Avg pChEMBL7.8
SourceBindingDB;ChEMBL
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB12128
Drug NameUlimorelin
CAS Number842131-33-3
Groups investigational
ATC Codes nan
DescriptionUlimorelin is a novel small molecule ghrelin agonist being developed by Tranzyme Pharma as a first-in-class treatment for both POI and diabetic gastroparesis, serious medical conditions in which motility of the GI tract is severely impaired.

Cross-references: BindingDB: 50359256 CHEMBL1963249 ChemSpider: 9701482 PubChem:11526696 PubChem:347828427 Wikipedia: Ulimorelin
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
Q92847 GHSR Homo sapiens Human PF00001 7.8 Ki ChEMBL
Q9UBU3 GHRL Homo sapiens Human PF04643 PF04644 7.8 Ki BindingDB
DrugBank Target Actions (1)
Target Gene Target Name Action Type
Q92847 GHSR Growth hormone secretagogue receptor type 1 agonist targets