Molecule Details
| InChIKey | WFPUBEDBBOGGIQ-UHFFFAOYSA-N |
|---|---|
| Compound Name | 7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline |
| Canonical SMILES | Clc1ccc2c(c1Cl)CNCC2 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.89 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB08550 |
|---|---|
| Drug Name | 7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline |
| CAS Number | 61563-24-4 |
| Groups | experimental |
| ATC Codes | nan |
| Description | Potent reversible inhibitor of phenylethanolamine N-methyltransferase. |
Categories: Antidepressive Agents Central Nervous System Depressants Enzyme Inhibitors Heterocyclic Compounds, Fused-Ring Isoquinolines Monoamine Oxidase Inhibitors Phenylethanolamine N-Methyltransferase, antagonists & inhibitors Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
Cross-references: BindingDB: 13014 ChEBI: 160129 CHEMBL287837 ChemSpider: 110451 PDB: SKA PubChem:123920 PubChem:99445021 ZINC: ZINC000024714117