N-[4-[(4-methyl-1,4-diazepan-1-yl)methyl]phenyl]-4-(thieno[2,3-d]pyrimidin-4-ylamino)-1H-pyrazole-5-carboxamide

InChIKey	`WEHOMMKULWQPKY-UHFFFAOYSA-N`
Compound Name	N-[4-[(4-methyl-1,4-diazepan-1-yl)methyl]phenyl]-4-(thieno[2,3-d]pyrimidin-4-ylamino)-1H-pyrazole-5-carboxamide
Canonical SMILES	`CN1CCCN(Cc2ccc(NC(=O)c3n[nH]cc3Nc3ncnc4sccc34)cc2)CC1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	8.84
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P36888	FLT3	Homo sapiens	Human	PF00047 PF07714	9.5	IC50	ChEMBL;BindingDB
P24941	CDK2	Homo sapiens	Human	PF00069	8.5	IC50	ChEMBL;BindingDB
P78396	CCNA1	Homo sapiens	Human	PF02984 PF00134 PF16500	8.5	IC50	ChEMBL