Molecule Details
InChIKeyWEGLOYDTDILXDA-OAHLLOKOSA-N
Compound NameBay-293
Canonical SMILESCNCc1ccccc1-c1csc([C@@H](C)Nc2nc(C)nc3cc(OC)c(OC)cc23)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)22
Pfam Stratification Cross-Family
Avg pChEMBL6.57
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (22)
Target Gene Organism Category Pfam pChEMBL Type Source
P01116 KRAS Homo sapiens Human PF00071 7.7 IC50 ChEMBL
Q07889 SOS1 Homo sapiens Human PF00617 PF00618 PF00621 PF22697 7.5 IC50 ChEMBL
P18825 ADRA2C Homo sapiens Human PF00001 6.9 Ki ChEMBL
P28223 HTR2A Homo sapiens Human PF00001 6.9 Ki ChEMBL
P25021 HRH2 Homo sapiens Human PF00001 6.8 Ki ChEMBL
P28482 MAPK1 Homo sapiens Human PF00069 6.8 IC50 ChEMBL
Q5BJF2 TMEM97 Homo sapiens Human PF05241 6.8 Ki ChEMBL
P28221 HTR1D Homo sapiens Human PF00001 6.7 Ki ChEMBL
P11229 CHRM1 Homo sapiens Human PF00001 6.6 Ki ChEMBL
P35368 ADRA1B Homo sapiens Human PF00001 6.6 Ki ChEMBL
P01111 NRAS Homo sapiens Human PF00071 6.5 IC50 ChEMBL
P01112 HRAS Homo sapiens Human PF00071 6.5 IC50 ChEMBL
P25100 ADRA1D Homo sapiens Human PF00001 6.5 Ki ChEMBL
P08913 ADRA2A Homo sapiens Human PF00001 6.4 Ki ChEMBL
P35348 ADRA1A Homo sapiens Human PF00001 6.4 Ki ChEMBL
Q01959 SLC6A3 Homo sapiens Human PF00209 6.3 Ki ChEMBL
P08172 CHRM2 Homo sapiens Human PF00001 6.3 Ki ChEMBL
P41595 HTR2B Homo sapiens Human PF00001 6.2 Ki ChEMBL
P23975 SLC6A2 Homo sapiens Human PF00209 6.0 Ki ChEMBL
P35462 DRD3 Homo sapiens Human PF00001 6.0 Ki ChEMBL
P08912 CHRM5 Homo sapiens Human PF00001 6.0 Ki ChEMBL
P20309 CHRM3 Homo sapiens Human PF00001 6.0 Ki ChEMBL