8-Chloro-6-(1-(4-fluoro-2-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-5-yl)-2H-benzo[b][1,4]oxazin-3(4H)-one

InChIKey	`WDYCDBMOJVBUFD-UHFFFAOYSA-N`
Compound Name	8-Chloro-6-(1-(4-fluoro-2-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-5-yl)-2H-benzo[b][1,4]oxazin-3(4H)-one
Canonical SMILES	`Cc1cc(F)ccc1-n1nc(C(F)(F)F)cc1-c1cc(Cl)c2c(c1)NC(=O)CO2`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	6.76
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P08235	NR3C2	Homo sapiens	Human	PF00104 PF00105	7.5	IC50	ChEMBL;BindingDB
P04150	NR3C1	Homo sapiens	Human	PF02155 PF00104 PF00105	6.7	IC50	ChEMBL;BindingDB
P06401	PGR	Homo sapiens	Human	PF00104 PF02161 PF00105	6.0	IC50	ChEMBL;BindingDB