InChIKey	WDJUZGPOPHTGOT-XUDUSOBPSA-N
Compound Name	Digitoxin
Canonical SMILES	C[C@H]1O[C@@H](O[C@H]2[C@@H](O)C[C@H](O[C@H]3[C@@H](O)C[C@H](O[C@H]4CC[C@@]5(C)[C@H](CC[C@@H]6[C@@H]5CC[C@]5(C)[C@@H](C7=CC(=O)OC7)CC[C@]65O)C4)O[C@@H]3C)O[C@@H]2C)C[C@H](O)[C@@H]1O
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	11
Pfam Stratification	Cross-Family
Avg pChEMBL	7.37
Source	BindingDB;ChEMBL

DrugBank ID	DB01396
Drug Name	Digitoxin
CAS Number	71-63-6
Groups	approved withdrawn
ATC Codes	C01AA04
Description	A cardiac glycoside sometimes used in place of digoxin. It has a longer half-life than digoxin; toxic effects, which are similar to those of digoxin, are longer lasting. (From Martindale, The Extra Pharmacopoeia, 30th ed, p665)

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Categories: Antiarrhythmic agents Carbohydrates Cardanolides Cardenolides Cardiac Glycosides Cardiac Therapy Cardiotonic Agents Cardiovascular Agents Compounds used in a research, industrial, or household setting Cytochrome P-450 CYP3A Substrates Cytochrome P-450 CYP3A4 Substrates Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index Cytochrome P-450 Substrates Digitalis Glycosides Enzyme Inhibitors Fused-Ring Compounds Glycosides Narrow Therapeutic Index Drugs P-glycoprotein substrates P-glycoprotein substrates with a Narrow Therapeutic Index Potential QTc-Prolonging Agents Protective Agents QTc Prolonging Agents Steroids

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Cross-references: BindingDB: 46356 ChEBI: 28544 CHEMBL254219 ChemSpider: 389987 Drugs Product Database (DPD): 10107 C06955 D00297 PDB: F9R PharmGKB: PA449316 PubChem:441207 PubChem:46506035 RxCUI: 3403 Therapeutic Targets Database: DAP000120 Wikipedia: Digitoxin ZINC: ZINC000095862733