Molecule Details
| InChIKey | WCKDYPHUXUBMEB-UHFFFAOYSA-N |
|---|---|
| Compound Name | N-[(1,2-Dihydro-6-methyl-2-oxo-4-propyl-3-pyridinyl)methyl]-1-(1-methylethyl)-6-[6-(4-methyl-1-piperazinyl)-3-pyridinyl]-1H-indazole-4-carboxamide |
| Canonical SMILES | CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(-c2ccc(N3CCN(C)CC3)nc2)cc2c1cnn2C(C)C |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 7 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.97 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (7)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q16576 | RBBP7 | Homo sapiens | Human | PF12265 PF00400 | 8.8 | IC50 | ChEMBL |
| O75530 | EED | Homo sapiens | Human | PF00400 | 8.4 | IC50 | ChEMBL |
| Q09028 | RBBP4 | Homo sapiens | Human | PF12265 PF00400 | 8.4 | IC50 | ChEMBL |
| Q15022 | SUZ12 | Homo sapiens | Human | PF09733 PF23320 | 8.4 | IC50 | ChEMBL |
| Q15910 | EZH2 | Homo sapiens | Human | PF21358 PF11616 PF18118 PF18264 PF00856 | 7.8 | IC50 | ChEMBL;BindingDB |
| Q6ZN18 | AEBP2 | Homo sapiens | Human | PF26014 | 7.0 | IC50 | ChEMBL |
| Q92800 | EZH1 | Homo sapiens | Human | PF21358 PF11616 PF18118 PF18264 PF00856 | 7.0 | IC50 | ChEMBL |