InChIKey	VZYCZNZBPPHOFY-UHFFFAOYSA-N
Compound Name	Thioproperazine
Canonical SMILES	CN1CCN(CCCN2c3ccccc3Sc3ccc(S(=O)(=O)N(C)C)cc32)CC1
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	9.13
Source	BindingDB

DrugBank ID	DB01622
Drug Name	Thioproperazine
CAS Number	316-81-4
Groups	approved
ATC Codes	N05AB08
Description	Thioproperazine is a potent neuroleptic with antipsychotic properties. Thioproperazine has a marked cataleptic and antiapomorphine activity associated with relatively slight sedative, hypothermic and spasmolytic effects. It is virtually without antiserotonin and hypotensive action and has no antihis...

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Categories: Adrenergic Antagonists Adrenergic alpha-1 Receptor Antagonists Adrenergic alpha-Antagonists Agents that produce hypertension Antidepressive Agents Antipsychotic Agents Antipsychotic Agents (First Generation [Typical]) Central Nervous System Depressants Dopamine Antagonists Dopamine D2 Receptor Antagonists Heterocyclic Compounds, Fused-Ring Nervous System Neurotoxic agents Phenothiazines Phenothiazines With Piperazine Structure Psycholeptics Serotonin 5-HT1 Receptor Antagonists Serotonin 5-HT2 Receptor Antagonists Serotonin Agents Serotonin Receptor Antagonists Sulfur Compounds

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Cross-references: BindingDB: 81793 ChEBI: 59120 CHEMBL609109 ChemSpider: 9058 Drugs Product Database (DPD): 7999 D08585 PharmGKB: PA164754875 PubChem:9429 PubChem:46507111 RxCUI: 10498 Wikipedia: Thioproperazine ZINC: ZINC000022446685