Molecule Details
| InChIKey | VZDPLMKEFMWBMM-UHFFFAOYSA-N |
|---|---|
| Compound Name | N'-methyl-N'-[[4-[3-(trifluoromethyl)phenyl]-1H-pyrrol-3-yl]methyl]ethane-1,2-diamine |
| Canonical SMILES | CN(CCN)Cc1c[nH]cc1-c1cccc(C(F)(F)F)c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.13 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q96LA8 | PRMT6 | Homo sapiens | Human | PF13649 PF22528 | 8.3 | IC50 | ChEMBL;BindingDB |
| Q9NR22 | PRMT8 | Homo sapiens | Human | PF06325 PF22528 | 7.6 | IC50 | ChEMBL;BindingDB |
| Q86X55 | CARM1 | Homo sapiens | Human | PF11531 PF06325 PF22528 | 6.8 | IC50 | ChEMBL;BindingDB |
| Q99873 | PRMT1 | Homo sapiens | Human | PF13649 PF22528 | 6.8 | IC50 | ChEMBL;BindingDB |
| O60678 | PRMT3 | Homo sapiens | Human | PF21137 PF21336 PF06325 PF22528 | 6.3 | Ki | ChEMBL;BindingDB |