Molecule Details
InChIKeyVZCCETWTMQHEPK-QNEBEIHSSA-N
Canonical SMILESCCCCC/C=C\C/C=C\C/C=C\CCCCC(=O)O
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL6.35
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB13854
Drug NameGamolenic acid
CAS Number506-26-3
Groups approved withdrawn
ATC Codes D11AX02 D11AX52
DescriptionGamolenic acid, or gamma-linolenic acid (γ-Linolenic acid) or GLA, is an essential fatty acid (EFA) comprised of 18 carbon atoms with three double bonds [F27] that is most commonly found in human milk and other botanical sources [A32848]. It is an omega-6 polyunsaturated fatty acid (PUFA) also refer...

Categories: Agents that reduce seizure threshold Dermatologicals Fatty Acids Fatty Acids, Essential Fatty Acids, Omega-6 Fatty Acids, Unsaturated Linolenic Acids Lipids
Cross-references: BindingDB: 50269532 ChEBI: 28661 CHEMBL464982 ChemSpider: 4444436 Drugs Product Database (DPD): 1350 C06426 D07213 RxCUI: 25605 Wikipedia: Gamma-Linolenic_acid ZINC: ZINC000003777423
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
Q07869 PPARA Homo sapiens Human PF00104 PF00105 6.6 IC50 ChEMBL;BindingDB
Q03181 PPARD Homo sapiens Human PF00104 PF00105 6.1 IC50 ChEMBL;BindingDB