8-N-(2,2-dimethylpropyl)-2-N-[2-methoxy-4-(4-methyl-1,2,4-triazol-3-yl)phenyl]pyrido[3,4-d]pyrimidine-2,8-diamine

InChIKey	`VZBGYKSZEPEEDD-UHFFFAOYSA-N`
Compound Name	8-N-(2,2-dimethylpropyl)-2-N-[2-methoxy-4-(4-methyl-1,2,4-triazol-3-yl)phenyl]pyrido[3,4-d]pyrimidine-2,8-diamine
Canonical SMILES	`COc1cc(-c2nncn2C)ccc1Nc1ncc2ccnc(NCC(C)(C)C)c2n1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	8.2
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P33981	TTK	Homo sapiens	Human	PF00069	8.7	IC50	ChEMBL;BindingDB
P20248	CCNA2	Homo sapiens	Human	PF02984 PF00134 PF16500	8.0	IC50	ChEMBL
P24941	CDK2	Homo sapiens	Human	PF00069	8.0	IC50	ChEMBL;BindingDB