[6-[2-(5-Bromopyrimidin-2-yl)oxyethoxy]-5-(4-methylphenyl)pyrimidin-4-yl]-[4-(1-hydroxy-2-methylpropan-2-yl)phenyl]sulfonylazanide

InChIKey	`VYAFCUPPLXQIIN-UHFFFAOYSA-N`
Compound Name	[6-[2-(5-Bromopyrimidin-2-yl)oxyethoxy]-5-(4-methylphenyl)pyrimidin-4-yl]-[4-(1-hydroxy-2-methylpropan-2-yl)phenyl]sulfonylazanide
Canonical SMILES	`Cc1ccc(-c2c([N-]S(=O)(=O)c3ccc(C(C)(C)CO)cc3)ncnc2OCCOc2ncc(Br)cn2)cc1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	9.28
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P25101	EDNRA	Homo sapiens	Human	PF00001	10.8	Ki	ChEMBL;BindingDB
P24530	EDNRB	Homo sapiens	Human	PF00001	7.7	IC50	ChEMBL;BindingDB