(2R)-N'-hydroxy-N-[(2S)-3-(1H-indol-3-yl)-1-oxo-1-(1,3-thiazol-2-ylmethylamino)propan-2-yl]-2-(2-methylpropyl)butanediamide

InChIKey	`VXXBOZLJRUCYLE-BEFAXECRSA-N`
Compound Name	(2R)-N'-hydroxy-N-[(2S)-3-(1H-indol-3-yl)-1-oxo-1-(1,3-thiazol-2-ylmethylamino)propan-2-yl]-2-(2-methylpropyl)butanediamide
Canonical SMILES	`CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCc1nccs1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	8.86
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P22894	MMP8	Homo sapiens	Human	PF00045 PF00413 PF01471	9.2	Ki	ChEMBL;BindingDB
P14780	MMP9	Homo sapiens	Human	PF00040 PF00045 PF00413	9.1	Ki	ChEMBL;BindingDB
P18843	nadE	Escherichia coli (strain K12)	Pathogen	PF02540	8.3	pIC50	TTD_MultiTarget