Molecule Details
InChIKeyVXLAKHWYGRKCGI-UHFFFAOYSA-N
Compound NameFn-1501
Canonical SMILESCN1CCN(Cc2ccc(NC(=O)c3n[nH]cc3Nc3ncnc4[nH]ccc34)cc2)CC1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)9
Pfam Stratification Cross-Family
Avg pChEMBL8.12
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB17383
Drug NameFN-1501
CAS Number1429515-59-2
Groups investigational
ATC Codes nan
Descriptionnan

Cross-references: BindingDB: 50270304 CHEMBL4077071 ChemSpider: 67886359
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
P36888 FLT3 Homo sapiens Human PF00047 PF07714 9.2 IC50 ChEMBL;BindingDB
P11802 CDK4 Homo sapiens Human PF00069 9.1 IC50 ChEMBL;BindingDB
P24385 CCND1 Homo sapiens Human PF02984 PF00134 8.7 IC50 ChEMBL;BindingDB
Q00534 CDK6 Homo sapiens Human PF00069 8.7 IC50 ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 8.6 IC50 ChEMBL;BindingDB
P78396 CCNA1 Homo sapiens Human PF02984 PF00134 PF16500 8.6 IC50 ChEMBL
O75909 CCNK Homo sapiens Human PF00134 PF21797 6.7 IC50 ChEMBL
Q9NYV4 CDK12 Homo sapiens Human PF00069 6.7 IC50 ChEMBL
Q14004 CDK13 Homo sapiens Human PF00069 6.7 IC50 ChEMBL
DrugBank Target Actions (4)
Target Gene Target Name Action Type
P11802 CDK4 Cyclin-dependent kinase 4 inhibitor targets
P24941 CDK2 Cyclin-dependent kinase 2 inhibitor targets
P36888 FLT3 Receptor-type tyrosine-protein kinase FLT3 inhibitor targets
Q00534 CDK6 Cyclin-dependent kinase 6 inhibitor targets