InChIKey	VWPOSFSPZNDTMJ-UCWKZMIHSA-N
Compound Name	Nadolol
Canonical SMILES	CC(C)(C)NCC(O)COc1cccc2c1C[C@H](O)[C@H](O)C2
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	7.34
Source	BindingDB

DrugBank ID	DB01203
Drug Name	Nadolol
CAS Number	42200-33-9
Groups	approved investigational
ATC Codes	C07BA12 C07AA12
Description	Nadolol is a nonselective beta adrenal receptor blocker that is used to lower blood pressure.[L7922,L7925] Nonselective beta adrenal receptor blockers may no longer be first line in the treatment of hypertension as newer generations of beta adrenal receptor blockers have higher selectivity and offer...

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Categories: Adrenergic Agents Adrenergic Antagonists Adrenergic beta-Antagonists Agents causing hyperkalemia Alcohols Amines Amino Alcohols Antiarrhythmic agents Antihypertensive Agents Antihypertensive Agents Indicated for Hypertension Autonomic Agents Beta Blocking Agents and Thiazides Beta Blocking Agents, Non-Selective Beta Blocking Agents, Non-Selective, and Thiazides Bradycardia-Causing Agents Cardiovascular Agents Cytochrome P-450 CYP2D6 Substrates Cytochrome P-450 Substrates Drugs causing inadvertant photosensitivity Drugs that are Mainly Renally Excreted Hypotensive Agents MATE 1 Substrates MATE 2 Substrates MATE substrates Negative Inotrope Neurotransmitter Agents P-glycoprotein substrates Peripheral Nervous System Agents Phenoxypropanolamines Photosensitizing Agents Propanolamines Propanols Sympatholytics

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Cross-references: BindingDB: 25766 ChEBI: 7444 CHEMBL649 ChemSpider: 35815 Drugs Product Database (DPD): 2099 Guide to Pharmacology: 554 IUPHAR: 554 D00432 PharmGKB: PA450573 PubChem:39147 PubChem:46505509 RxCUI: 7226 Therapeutic Targets Database: DAP000122 Wikipedia: Nadolol