Molecule Details
InChIKeyVWELCPLMPPEKOL-UHFFFAOYSA-N
Compound NameBms-695735
Canonical SMILESCc1cc(C2CCN(CCCF)CC2)cc2[nH]c(-c3c(NCCn4cc(Cl)cn4)cc[nH]c3=O)nc12
Clinical Status Clinical Multi-Target
Targets (Human+Pathogen)9
Pfam Stratification Cross-Family
Avg pChEMBL6.86
SourceChEMBL;BindingDB;TTD_MultiTarget
2D Structure
2D structure
Activity Profile
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
P06729 CD2 Homo sapiens Human PF05790 PF07686 7.5 pIC50 TTD_MultiTarget
P08069 IGF1R Homo sapiens Human PF00757 PF07714 PF01030 7.5 IC50 ChEMBL;BindingDB
P04626 ERBB2 Homo sapiens Human PF00757 PF14843 PF07714 PF01030 PF21314 7.0 pIC50 TTD_MultiTarget
P08581 MET Homo sapiens Human PF07714 PF01437 PF01403 PF01833 7.0 pIC50 TTD_MultiTarget
P06239 LCK Homo sapiens Human PF07714 PF00017 PF00018 6.8 IC50 ChEMBL
Q05397 PTK2 Homo sapiens Human PF21477 PF00373 PF18038 PF03623 PF07714 6.8 IC50 ChEMBL
P11362 FGFR1 Homo sapiens Human PF07679 PF00047 PF07714 6.4 pIC50 TTD_MultiTarget
P35968 KDR Homo sapiens Human PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854 6.4 IC50 ChEMBL
Q08881 ITK Homo sapiens Human PF00779 PF00169 PF07714 PF00017 PF00018 6.4 IC50 ChEMBL