Molecule Details
| InChIKey | VWCSZVWZRTZNCH-UHFFFAOYSA-N |
|---|---|
| Compound Name | 5-[4-[(4-chlorophenyl)methyl]-5-methyl-1,2,4-triazol-3-yl]-3-methyl-2H-indazole |
| Canonical SMILES | Cc1n[nH]c2ccc(-c3nnc(C)n3Cc3ccc(Cl)cc3)cc12 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 8 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.73 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (8)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P24863 | CCNC | Homo sapiens | Human | PF16899 PF00134 | 9.3 | IC50 | ChEMBL |
| P49336 | CDK8 | Homo sapiens | Human | PF00069 | 9.3 | IC50 | ChEMBL |
| P49760 | CLK2 | Homo sapiens | Human | PF00069 | 7.4 | Kd | ChEMBL |
| Q9NRM7 | LATS2 | Homo sapiens | Human | PF00069 PF00433 | 7.4 | Kd | ChEMBL |
| P49759 | CLK1 | Homo sapiens | Human | PF00069 | 7.4 | Kd | ChEMBL |
| P49841 | GSK3B | Homo sapiens | Human | PF00069 | 7.2 | Kd | ChEMBL |
| P49840 | GSK3A | Homo sapiens | Human | PF00069 | 6.9 | Kd | ChEMBL |
| Q9Y6M4 | CSNK1G3 | Homo sapiens | Human | PF12605 PF00069 | 6.8 | Kd | ChEMBL |