Molecule Details
InChIKeyVWCMAGONQJHIJZ-LPHOPBHVSA-N
Compound NameN-((3R,4S)-4-((6-amino-4-methylpyridin-2-yl)methyl)pyrrolidin-3-yl)-N'-(3-chlorobenzyl)ethane-1,2-diamine
Canonical SMILESCc1cc(N)nc(C[C@H]2CNC[C@@H]2NCCNCc2cccc(Cl)c2)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL8.31
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB08019
Drug NameN-{(3R,4S)-4-[(6-amino-4-methylpyridin-2-yl)methyl]pyrrolidin-3-yl}-N'-(3-chlorobenzyl)ethane-1,2-diamine
CAS Numbernan
Groups experimental
ATC Codes nan
Descriptionnan

Cross-references: BindingDB: 29235 CHEMBL526688 ChemSpider: 24721145 PDB: JI7 PubChem:25021186 PubChem:99444490 ZINC: ZINC000039036704
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P29475 NOS1 Homo sapiens Human PF00667 PF00258 PF00175 PF02898 PF00595 9.6 Ki ChEMBL
P29474 NOS3 Homo sapiens Human PF00667 PF00258 PF00175 PF02898 7.0 Ki ChEMBL
DrugBank Target Actions (2)
Target Gene Target Name Action Type
P29474 NOS3 Nitric oxide synthase 3 binder targets
P29475 NOS1 Nitric oxide synthase 1 binder targets