4-[[3-[4-(3,7-Difluoroisoquinolin-1-yl)piperazin-1-yl]-2-hydroxypropyl]amino]-6-fluoro-1,3-benzoxazin-2-one

InChIKey	`VVEJKTJFDNJXPE-UHFFFAOYSA-N`
Compound Name	4-[[3-[4-(3,7-Difluoroisoquinolin-1-yl)piperazin-1-yl]-2-hydroxypropyl]amino]-6-fluoro-1,3-benzoxazin-2-one
Canonical SMILES	`O=c1nc(NCC(O)CN2CCN(c3nc(F)cc4ccc(F)cc34)CC2)c2cc(F)ccc2o1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	7.55
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P20831	gyrA	Staphylococcus aureus	Pathogen	PF03989 PF00521	7.7	IC50	ChEMBL;BindingDB
P0C1U9	parC	Staphylococcus aureus	Pathogen	PF03989 PF00521	7.4	IC50	ChEMBL;BindingDB