3-(4-(6,7-dimethoxyquinolin-4-yloxy)-3-fluorophenylamino)-4,4,4-trifluoro-N-phenylbutanamide

InChIKey	`VVCJSJLTDUKFKI-UHFFFAOYSA-N`
Compound Name	3-(4-(6,7-dimethoxyquinolin-4-yloxy)-3-fluorophenylamino)-4,4,4-trifluoro-N-phenylbutanamide
Canonical SMILES	`COc1cc2nccc(Oc3ccc(NC(CC(=O)Nc4ccccc4)C(F)(F)F)cc3F)c2cc1OC`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	7.52
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P08581	MET	Homo sapiens	Human	PF07714 PF01437 PF01403 PF01833	7.5	pIC50	TTD_MultiTarget
P35968	KDR	Homo sapiens	Human	PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854	7.5	IC50	ChEMBL;BindingDB