Molecule Details
InChIKeyVUVUVNZRUGEAHB-CYBMUJFWSA-N
Compound NameI-Bet151
Canonical SMILESCOc1cc2c(cc1-c1c(C)noc1C)ncc1[nH]c(=O)n([C@H](C)c3ccccn3)c12
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)5
Pfam Stratification Cross-Family
Avg pChEMBL7.01
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (5)
Target Gene Organism Category Pfam pChEMBL Type Source
Q15059 BRD3 Homo sapiens Human PF17035 PF00439 7.2 IC50 ChEMBL;BindingDB
P13500 CCL2 Homo sapiens Human PF00048 7.0 IC50 ChEMBL
O60885 BRD4 Homo sapiens Human PF17035 PF17105 PF00439 7.0 IC50 ChEMBL;BindingDB
Q58F21 BRDT Homo sapiens Human PF17035 PF17105 PF00439 6.9 IC50 ChEMBL;BindingDB
P25440 BRD2 Homo sapiens Human PF17035 PF00439 6.9 IC50 ChEMBL;BindingDB