Molecule Details
InChIKeyVURLRACCOCGFDB-UHFFFAOYSA-N
Compound NameSphinx31
Canonical SMILESO=C(Nc1cc(C(F)(F)F)ccc1N1CCN(Cc2ccccn2)CC1)c1ccc(-c2ccncc2)o1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)6
Pfam Stratification Cross-Family
Avg pChEMBL6.8
SourceBindingDB;ChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (6)
Target Gene Organism Category Pfam pChEMBL Type Source
Q96SB4 SRPK1 Homo sapiens Human PF00069 8.2 IC50 ChEMBL;BindingDB
Q9UPE1 SRPK3 Homo sapiens Human PF00069 6.8 IC50 ChEMBL
P78362 SRPK2 Homo sapiens Human PF00069 6.6 IC50 ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.6 IC50 ChEMBL
Q12809 KCNH2 Homo sapiens Human PF00027 PF00520 PF13426 6.5 IC50 BindingDB
P49759 CLK1 Homo sapiens Human PF00069 6.1 IC50 ChEMBL