Molecule Details
| InChIKey | VUODRPPTYLBGFM-CMDGGOBGSA-N |
|---|---|
| Compound Name | Bms453 |
| Canonical SMILES | CC1(C)CC=C(c2ccccc2)c2cc(/C=C/c3ccc(C(=O)O)cc3)ccc21 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.71 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P10276 | RARA | Homo sapiens | Human | PF00104 PF00105 | 8.1 | IC50 | ChEMBL;BindingDB |
| P19793 | RXRA | Homo sapiens | Human | PF00104 PF11825 PF00105 | 7.8 | Ki | ChEMBL |
| P13631 | RARG | Homo sapiens | Human | PF00104 PF00105 | 7.8 | IC50 | ChEMBL |
| P10826 | RARB | Homo sapiens | Human | PF00104 PF00105 | 7.2 | IC50 | ChEMBL |