Molecule Details
| InChIKey | VTUTUCVVSXMISL-UHFFFAOYSA-N |
|---|---|
| Compound Name | 2-[(4-chloro-3-methoxyphenyl)methoxy]-1H-pyrrolo[3,2-b]pyridine-7-carboxylic acid |
| Canonical SMILES | COc1cc(COc2cc3nccc(C(=O)O)c3[nH]2)ccc1Cl |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.33 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| O75164 | KDM4A | Homo sapiens | Human | PF02373 PF02375 PF13831 PF18104 PF13832 | 7.0 | IC50 | ChEMBL;BindingDB |
| P29375 | KDM5A | Homo sapiens | Human | PF01388 PF02373 PF02375 PF21323 PF00628 PF08429 PF02928 | 6.0 | IC50 | ChEMBL;BindingDB |
| Q9UGL1 | KDM5B | Homo sapiens | Human | PF01388 PF02373 PF02375 PF21323 PF00628 PF08429 PF02928 | 6.0 | IC50 | ChEMBL;BindingDB |