Molecule Details
| InChIKey | VTKAGCUSZSWYBW-SSZFMOIBSA-N |
|---|---|
| Compound Name | (NZ)-5-chloro-N-(4-chloro-5-isopropyl-3-methyl-thiazol-2-ylidene)-2-hydroxy-benzenesulfonamide |
| Canonical SMILES | CC(C)c1s/c(=N\S(=O)(=O)c2cc(Cl)ccc2O)n(C)c1Cl |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.09 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P04585 | gag-pol | Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) | Pathogen | PF00540 PF19317 PF00552 PF02022 PF00075 PF00665 PF00077 PF00078 PF06815 PF06817 PF00098 | 7.7 | IC50 | BindingDB |
| Q72547 | pol | Human immunodeficiency virus type 1 | Pathogen | PF00075 PF00078 PF06815 PF06817 | 6.8 | IC50 | ChEMBL |
| Q9WJQ2 | reverse transcriptase | Human immunodeficiency virus type 1 | Pathogen | PF00078 | 6.8 | IC50 | BindingDB |