Molecule Details
InChIKeyVRQMAABPASPXMW-UHFFFAOYSA-N
Compound NameN-[5-[2-(3,5-Dimethoxyphenyl)ethyl]-2H-pyrazol-3-yl]-4-(3,5-dimethylpiperazin-1-yl)benzamide
Canonical SMILESCOc1cc(CCc2cc(NC(=O)c3ccc(N4CC(C)NC(C)C4)cc3)n[nH]2)cc(OC)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)10
Pfam Stratification Cross-Family
Avg pChEMBL7.26
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (10)
Target Gene Organism Category Pfam pChEMBL Type Source
P11362 FGFR1 Homo sapiens Human PF07679 PF00047 PF07714 8.7 Kd ChEMBL
Q9Y4K4 MAP4K5 Homo sapiens Human PF00780 PF00069 8.2 Kd ChEMBL
P07949 RET Homo sapiens Human PF00028 PF07714 PF17756 PF17812 PF17813 PF22540 7.5 Kd ChEMBL
Q8IVH8 MAP4K3 Homo sapiens Human PF00780 PF00069 7.3 Kd ChEMBL
Q08345 DDR1 Homo sapiens Human PF21114 PF00754 PF07714 7.2 Kd ChEMBL
Q12851 MAP4K2 Homo sapiens Human PF00780 PF00069 7.0 Kd ChEMBL
Q07912 TNK2 Homo sapiens Human PF09027 PF11555 PF07714 PF22931 PF14604 6.8 Kd ChEMBL
Q9BQI3 EIF2AK1 Homo sapiens Human PF22949 PF00069 6.8 Kd ChEMBL
P09619 PDGFRB Homo sapiens Human PF00047 PF13927 PF25305 PF07714 6.5 Kd ChEMBL
Q92918 MAP4K1 Homo sapiens Human PF00780 PF00069 6.5 Kd ChEMBL