Molecule Details
InChIKeyVRIFJAKXSBXYFZ-UHFFFAOYSA-N
Compound Name4-[(4-ethyl-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino]-N-propylbenzamide
Canonical SMILESCCCNC(=O)c1ccc(Nc2nc(CC)c3cc[nH]c3n2)cc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)8
Pfam Stratification Cross-Family
Avg pChEMBL6.44
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (8)
Target Gene Organism Category Pfam pChEMBL Type Source
Q5S007 LRRK2 Homo sapiens Human PF23745 PF23744 PF23748 PF16095 PF25497 PF13855 PF00069 PF08477 7.5 Ki ChEMBL
P35968 KDR Homo sapiens Human PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854 6.7 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 6.5 Ki ChEMBL
P45983 MAPK8 Homo sapiens Human PF00069 6.4 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.3 Ki ChEMBL
P07949 RET Homo sapiens Human PF00028 PF07714 PF17756 PF17812 PF17813 PF22540 6.1 Ki ChEMBL
O60674 JAK2 Homo sapiens Human PF18379 PF18377 PF17887 PF07714 PF21990 6.0 Ki ChEMBL
P48729 CSNK1A1 Homo sapiens Human PF00069 6.0 Ki ChEMBL