(2S)-2-[[2-(azepan-1-yl)acetyl]amino]-4-methyl-N-[(2S)-1-[[(2S)-1-[(2R)-2-methyloxiran-2-yl]-4-(4-methylphenyl)-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]pentanamide

InChIKey	`VQYDMTVFQVMOIH-FNNAEHFOSA-N`
Compound Name	(2S)-2-[[2-(azepan-1-yl)acetyl]amino]-4-methyl-N-[(2S)-1-[[(2S)-1-[(2R)-2-methyloxiran-2-yl]-4-(4-methylphenyl)-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]pentanamide
Canonical SMILES	`Cc1ccc(CC[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(C)C)NC(=O)CN2CCCCCC2)C(=O)[C@@]2(C)CO2)cc1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	4
Pfam Stratification	Homologous
Avg pChEMBL	6.57
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P40306	PSMB10	Homo sapiens	Human	PF12465 PF00227	7.2	IC50	ChEMBL;BindingDB
P28062	PSMB8	Homo sapiens	Human	PF00227	6.5	IC50	ChEMBL;BindingDB
P49721	PSMB2	Homo sapiens	Human	PF00227	6.4	IC50	ChEMBL;BindingDB
P28074	PSMB5	Homo sapiens	Human	PF00227	6.3	IC50	ChEMBL;BindingDB