Molecule Details
| InChIKey | VQQVWGVXDIPORV-UHFFFAOYSA-N |
|---|---|
| Compound Name | Tryptanthrin |
| Canonical SMILES | O=C1c2ccccc2-n2c1nc1ccccc1c2=O |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.94 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P14902 | IDO1 | Homo sapiens | Human | PF01231 | 7.3 | IC50 | ChEMBL;BindingDB |
| P35354 | PTGS2 | Homo sapiens | Human | PF03098 | 7.2 | IC50 | ChEMBL;BindingDB |
| P09917 | ALOX5 | Homo sapiens | Human | PF00305 PF01477 | 6.8 | IC50 | ChEMBL;BindingDB |
| P48775 | TDO2 | Homo sapiens | Human | PF03301 | 6.5 | IC50 | ChEMBL;BindingDB |