Molecule Details
| InChIKey | VQDRNQBRRSNVOR-UHFFFAOYSA-N |
|---|---|
| Compound Name | 3-[7-[[4-[[4-(2,4-difluorophenyl)piperazin-1-yl]methyl]phenyl]methoxy]-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione |
| Canonical SMILES | O=C1CCC(N2Cc3c(OCc4ccc(CN5CCN(c6ccc(F)cc6F)CC5)cc4)cccc3C2=O)C(=O)N1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.61 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P25100 | ADRA1D | Homo sapiens | Human | PF00001 | 7.8 | IC50 | ChEMBL |
| P35348 | ADRA1A | Homo sapiens | Human | PF00001 | 7.8 | IC50 | ChEMBL;BindingDB |
| P35368 | ADRA1B | Homo sapiens | Human | PF00001 | 7.8 | IC50 | ChEMBL |
| Q16531 | DDB1 | Homo sapiens | Human | PF10433 PF23726 PF03178 | 7.3 | IC50 | ChEMBL |
| Q96SW2 | CRBN | Homo sapiens | Human | PF02190 PF03226 | 7.3 | IC50 | ChEMBL |