Molecule Details
InChIKeyVPCSYAVXDAUHLT-UHFFFAOYSA-N
Canonical SMILESCC(C)c1cc(Oc2c(Br)cc(NC(=O)CC(=O)O)cc2Br)ccc1O
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL8.7
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB05035
Drug NameEprotirome
CAS Number355129-15-6
Groups investigational
ATC Codes nan
DescriptionEprotirome which is a compound with promising properties for treatment of obesity and dyslipidemia. Eprotirome increases the body’s energy consumption and reduces body weight and markedly reduces blood lipids and blood glucose.

Categories: Amides Amines Aniline Compounds
Cross-references: BindingDB: 50385105 CHEMBL2035874 ChemSpider: 8475344 PDB: 64L PubChem:10299876 PubChem:347827705 ZINC: ZINC000001494227
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P10828 THRB Homo sapiens Human PF00104 PF00105 9.4 Ki ChEMBL;BindingDB
P10827 THRA Homo sapiens Human PF00104 PF00105 8.0 Ki ChEMBL;BindingDB
DrugBank Target Actions (2)
Target Gene Target Name Action Type
P10827 THRA Thyroid hormone receptor alpha binder targets
P10828 THRB Thyroid hormone receptor beta binder targets