Molecule Details
InChIKeyVOYZWDQJVPQGCO-UHFFFAOYSA-N
Compound Name2-(2,6-Dimethoxy-4-(7-(1-methyl-1H-pyrazol-4-yl)imidazo[1,2-a]pyridin-3-yl)phenyl)-5-ethyl-1,3,4-oxadiazole
Canonical SMILESCCc1nnc(-c2c(OC)cc(-c3cnc4cc(-c5cnn(C)c5)ccn34)cc2OC)o1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)9
Pfam Stratification Cross-Family
Avg pChEMBL7.81
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9H0K1 SIK2 Homo sapiens Human PF00069 PF23312 9.4 IC50 ChEMBL;BindingDB
Q9Y2K2 SIK3 Homo sapiens Human PF00069 PF23312 8.9 IC50 ChEMBL;BindingDB
P57059 SIK1 Homo sapiens Human PF00069 PF23312 8.2 IC50 ChEMBL;BindingDB
P16234 PDGFRA Homo sapiens Human PF07679 PF25305 PF07714 7.8 IC50 ChEMBL
P41240 CSK Homo sapiens Human PF07714 PF00017 PF00018 7.3 IC50 ChEMBL
Q9UKE5 TNIK Homo sapiens Human PF00780 PF00069 7.2 IC50 ChEMBL
Q9UHD2 TBK1 Homo sapiens Human PF00069 PF18394 PF18396 7.2 IC50 ChEMBL
Q14164 IKBKE Homo sapiens Human PF00069 PF18394 PF18396 7.2 IC50 ChEMBL
P00519 ABL1 Homo sapiens Human PF08919 PF07714 PF00017 PF00018 7.1 IC50 ChEMBL