InChIKey	VOVIALXJUBGFJZ-KWVAZRHASA-N
Compound Name	Budesonide
Canonical SMILES	CCCC1O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@]2(C(=O)CO)O1
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	4
Pfam Stratification	Cross-Family
Avg pChEMBL	8.31
Source	BindingDB;ChEMBL

DrugBank ID	DB01222
Drug Name	Budesonide
CAS Number	51333-22-3
Groups	approved investigational
ATC Codes	R03AK15 R03AL11 D07AC09 R01AD05 R03AK07 A07EA06 R03BA02 R03AK12
Description	Budesonide is a glucocorticoid that is a mix of the 22R and 22S epimer used to treat inflammatory conditions of the lungs and intestines such as asthma, COPD, Crohn's disease, and ulcerative colitis.[A188529,A188532] Budesonide was granted FDA approval on 14 February 1994.[L10598] It is also availab...

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Categories: Adrenal Cortex Hormones Adrenals Agents to Treat Airway Disease Alimentary Tract and Metabolism Anti-Asthmatic Agents Anti-Inflammatory Agents Antidiarrheals, Intestinal Antiinflammatory/antiinfective Agents Autonomic Agents BSEP/ABCB11 Substrates Bronchodilator Agents Corticosteroid Hormone Receptor Agonists Corticosteroids Corticosteroids Acting Locally Corticosteroids for Systemic Use Corticosteroids, Dermatological Preparations Corticosteroids, Potent (Group III) Cytochrome P-450 CYP2A6 Inducers Cytochrome P-450 CYP2B6 Inducers Cytochrome P-450 CYP2B6 Inducers (strength unknown) Cytochrome P-450 CYP2C19 Inducers Cytochrome P-450 CYP2C19 Inducers (strength unknown) Cytochrome P-450 CYP2C8 Inducers Cytochrome P-450 CYP2C8 Inducers (strength unknown) Cytochrome P-450 CYP2C9 Inducers Cytochrome P-450 CYP2C9 Inducers (strength unknown) Cytochrome P-450 CYP3A Inducers Cytochrome P-450 CYP3A Substrates Cytochrome P-450 CYP3A4 Inducers Cytochrome P-450 CYP3A4 Inducers (strength unknown) Cytochrome P-450 CYP3A4 Substrates Cytochrome P-450 CYP3A5 Inducers Cytochrome P-450 CYP3A5 Inducers (moderate) Cytochrome P-450 Enzyme Inducers Cytochrome P-450 Substrates Dermatologicals Drugs for Obstructive Airway Diseases Drugs that are Mainly Renally Excreted Fused-Ring Compounds Hormones Hormones, Hormone Substitutes, and Hormone Antagonists Immunosuppressive Agents Intestinal Antiinflammatory Agents Nasal Preparations OAT3/SLC22A8 Substrates P-glycoprotein substrates Peripheral Nervous System Agents Pregnanes Pregnenediones Pregnenes Respiratory System Agents Steroids

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Cross-references: BindingDB: 50354850 ChEBI: 3207 CHEMBL1370 ChemSpider: 4444479 Drugs Product Database (DPD): 7581 D00246 PharmGKB: PA448681 PubChem:5281004 PubChem:46504869 RxCUI: 19831 Therapeutic Targets Database: DAP000320 Wikipedia: Budesonide