Molecule Details
InChIKeyVOTCBKOYCAMWBJ-CELWHGEPSA-N
Compound Name10-O-[(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a-hydroxy-7-oxo-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-9-yl] 1-O-[(1R,9R)-17-(cyclobutylmethyl)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-4-yl] decanedioate
Canonical SMILESO=C(CCCCCCCCC(=O)Oc1ccc2c3c1O[C@H]1C(=O)CC[C@@]4(O)[C@@H](C2)N(CC2CC2)CC[C@]314)Oc1ccc2c(c1)[C@@]13CCCCC1[C@@H](C2)N(CC1CCC1)CC3
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Homologous
Avg pChEMBL8.64
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
P41145 OPRK1 Homo sapiens Human PF00001 9.9 Ki ChEMBL;BindingDB
P35372 OPRM1 Homo sapiens Human PF00001 8.2 IC50 ChEMBL;BindingDB
P41143 OPRD1 Homo sapiens Human PF00001 7.8 Ki ChEMBL;BindingDB