8-(4,4-Dimethyl-1,2,3,4-tetrahydronaphthalen-1-yl)-1-phenyl-3-[2-(pyrrolidin-1-yl)ethyl]-1,3,8-triazaspiro[4.5]decan-4-one

InChIKey	`VOSNJKFVBDSLTN-UHFFFAOYSA-N`
Compound Name	8-(4,4-Dimethyl-1,2,3,4-tetrahydronaphthalen-1-yl)-1-phenyl-3-[2-(pyrrolidin-1-yl)ethyl]-1,3,8-triazaspiro[4.5]decan-4-one
Canonical SMILES	`CC1(C)CCC(N2CCC3(CC2)C(=O)N(CCN2CCCC2)CN3c2ccccc2)c2ccccc21`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	7.59
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P41146	OPRL1	Homo sapiens	Human	PF00001	8.8	Ki	ChEMBL;BindingDB
P35372	OPRM1	Homo sapiens	Human	PF00001	7.2	Ki	ChEMBL;BindingDB
P41145	OPRK1	Homo sapiens	Human	PF00001	6.8	Ki	ChEMBL;BindingDB