5-(2-Amino-pyrimidin-4-yl)-2-phenyl-1H-pyrrole-3-carboxamide

InChIKey	`VOQXQYXTZZHYBF-UHFFFAOYSA-N`
Compound Name	5-(2-Amino-pyrimidin-4-yl)-2-phenyl-1H-pyrrole-3-carboxamide
Canonical SMILES	`NC(=O)c1cc(-c2ccnc(N)n2)[nH]c1-c1ccccc1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	7
Pfam Stratification	Cross-Family
Avg pChEMBL	6.71
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
O00311	CDC7	Homo sapiens	Human	PF00069	7.7	IC50	ChEMBL;BindingDB
P50750	CDK9	Homo sapiens	Human	PF00069	6.4	IC50	ChEMBL
O60563	CCNT1	Homo sapiens	Human	PF00134 PF21797	6.4	IC50	ChEMBL;BindingDB
Q7L7X3	TAOK1	Homo sapiens	Human	PF00069	6.4	IC50	ChEMBL;BindingDB
P06493	CDK1	Homo sapiens	Human	PF00069	Clinical	TTD_MultiTarget	TTD_MultiTarget
P18505	GABRB1	Homo sapiens	Human	PF02931 PF02932	Clinical	TTD_MultiTarget	TTD_MultiTarget
P24941	CDK2	Homo sapiens	Human	PF00069	Clinical	TTD_MultiTarget	TTD_MultiTarget