Molecule Details
| InChIKey | VOFLAIHEELWYGO-UHFFFAOYSA-N |
|---|---|
| Canonical SMILES | O=C(c1cc(Cl)c(O)c(Cl)c1)N1CS(=O)(=O)c2ccccc21 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 2 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.43 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB16145 |
|---|---|
| Drug Name | Dotinurad |
| CAS Number | 1285572-51-1 |
| Groups | investigational |
| ATC Codes | nan |
| Description | Dotinurad is under investigation in clinical trial NCT03372200 (Febuxostat-controlled, Double-blind, Comparative Study of FYU-981 in Hyperuricemia With or Without Gout). |
Categories: Antigout Preparations Antirheumatic Agents Heterocyclic Compounds, Fused-Ring Thiazoles Uricosuric Agents
Cross-references: ChemSpider: 59718651 PDB: A1AIK
Target Activities (2)
DrugBank Target Actions (1)
| Target | Gene | Target Name | Action | Type |
|---|---|---|---|---|
| Q96S37 | SLC22A12 | Solute carrier family 22 member 12 | inhibitor | targets |