4-[(5-Bromo-2-{[1-(3-chlorobenzyl)piperidin-4-yl]amino}pyrimidin-4-yl)oxy]-3,5-dimethylbenzonitrile

InChIKey	`VNXLEXMHJHNNFA-UHFFFAOYSA-N`
Compound Name	4-[(5-Bromo-2-{[1-(3-chlorobenzyl)piperidin-4-yl]amino}pyrimidin-4-yl)oxy]-3,5-dimethylbenzonitrile
Canonical SMILES	`Cc1cc(C#N)cc(C)c1Oc1nc(NC2CCN(Cc3cccc(Cl)c3)CC2)ncc1Br`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	6.63
Source	BindingDB;ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q9WJQ2	reverse transcriptase	Human immunodeficiency virus type 1	Pathogen	PF00078	6.6	IC50	BindingDB
Q72547	pol	Human immunodeficiency virus type 1	Pathogen	PF00075 PF00078 PF06815 PF06817	6.6	IC50	ChEMBL