Molecule Details
InChIKeyVNGYQBMDQMDALH-UHFFFAOYSA-N
Compound Name11,12-dihydro-2H-cyclopenta[4,5]thieno[3,2-e]bis([1,2,4]triazolo)[4,3-a:4',3'-c]pyrimidine-3,7(6H,10H)-dithione
Canonical SMILESS=c1[nH]nc2c3c4c(sc3n3c(=S)[nH]nc3n12)CCC4
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)25
Pfam Stratification Cross-Family
Avg pChEMBL6.63
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (25)
Target Gene Organism Category Pfam pChEMBL Type Source
Q86V86 PIM3 Homo sapiens Human PF00069 8.1 Ki ChEMBL
P11309 PIM1 Homo sapiens Human PF00069 7.6 Ki ChEMBL
O43293 DAPK3 Homo sapiens Human PF00069 7.5 Ki ChEMBL
Q9P1W9 PIM2 Homo sapiens Human PF00069 7.5 Ki ChEMBL
P00519 ABL1 Homo sapiens Human PF08919 PF07714 PF00017 PF00018 7.1 Ki ChEMBL
P68400 CSNK2A1 Homo sapiens Human PF00069 7.1 Ki ChEMBL
P06241 FYN Homo sapiens Human PF07714 PF00017 PF00018 7.0 Ki ChEMBL
P51812 RPS6KA3 Homo sapiens Human PF00069 PF00433 6.7 Ki ChEMBL
Q13557 CAMK2D Homo sapiens Human PF08332 PF00069 6.7 Ki ChEMBL
P08922 ROS1 Homo sapiens Human PF00041 PF07714 6.6 Ki ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 6.5 Ki ChEMBL
Q9H2X6 HIPK2 Homo sapiens Human PF00069 6.5 Ki ChEMBL
P04629 NTRK1 Homo sapiens Human PF13855 PF16920 PF07714 PF18613 6.4 Ki ChEMBL
P23443 RPS6KB1 Homo sapiens Human PF00069 PF00433 6.4 Ki ChEMBL
P53350 PLK1 Homo sapiens Human PF00069 PF00659 6.4 Ki ChEMBL
Q9H4B4 PLK3 Homo sapiens Human PF00069 PF00659 6.4 Ki ChEMBL
O75582 RPS6KA5 Homo sapiens Human PF00069 PF00433 6.3 Ki ChEMBL
Q96SB4 SRPK1 Homo sapiens Human PF00069 6.3 Ki ChEMBL
Q9BZL6 PRKD2 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.3 Ki ChEMBL
P51451 BLK Homo sapiens Human PF07714 PF00017 PF00018 6.2 Ki ChEMBL
O00311 CDC7 Homo sapiens Human PF00069 6.1 Ki ChEMBL
O95819 MAP4K4 Homo sapiens Human PF00780 PF00069 6.1 Ki ChEMBL
P35916 FLT4 Homo sapiens Human PF07679 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854 6.0 Ki ChEMBL
Q13555 CAMK2G Homo sapiens Human PF08332 PF00069 6.0 Ki ChEMBL
Q8NE63 HIPK4 Homo sapiens Human PF00069 6.0 Ki ChEMBL