InChIKey	VMZMNAABQBOLAK-DBILLSOUSA-N
Compound Name	Pasireotide
Canonical SMILES	NCCCC[C@@H]1NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](c2ccccc2)NC(=O)[C@@H]2C[C@@H](OC(=O)NCCN)CN2C(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccc(OCc3ccccc3)cc2)NC1=O
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	4
Pfam Stratification	Homologous
Avg pChEMBL	9.05
Source	ChEMBL;BindingDB

DrugBank ID	DB06663
Drug Name	Pasireotide
CAS Number	396091-73-9
Groups	approved investigational
ATC Codes	H01CB05
Description	Pasireotide is a synthetic long-acting cyclic hexapeptide with somatostatin-like activity. It is marketed as a diaspartate salt called Signifor, which is used in the treatment of Cushing's disease.

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Categories: Amino Acids, Peptides, and Proteins Bradycardia-Causing Agents Cytochrome P-450 CYP3A Inhibitors Cytochrome P-450 CYP3A4 Inhibitors Cytochrome P-450 CYP3A4 Inhibitors (weak) Cytochrome P-450 Enzyme Inhibitors Hormones Hormones, Hormone Substitutes, and Hormone Antagonists Hyperglycemia-Associated Agents Hypoglycemia-Associated Agents Hypothalamic Hormones Nerve Tissue Proteins Neuropeptides Pancreatic Hormones Peptide Hormones Peptides Pituitary Hormone Release Inhibiting Hormones Pituitary and Hypothalamic Hormones and Analogues Potential QTc-Prolonging Agents Proteins QTc Prolonging Agents Somatostatin Agonists Somatostatin Receptor Agonists Somatostatin and Analogues Systemic Hormonal Preparations, Excl. Sex Hormones and Insulins

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Cross-references: BindingDB: 50474236 ChEBI: 72312 CHEMBL3349607 ChemSpider: 8117062 Drugs Product Database (DPD): 22149 D10147 PubChem:9941444 PubChem:175427082 RxCUI: 1364105 Wikipedia: Pasireotide