Molecule Details
InChIKeyVMMKGHQPQIEGSQ-UHFFFAOYSA-N
Compound NameMinodronic Acid
Canonical SMILESO=P(O)(O)C(O)(Cc1cnc2ccccn12)P(=O)(O)O
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Homologous
Avg pChEMBL7.12
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB06548
Drug NameMinodronic acid
CAS Number180064-38-4
Groups investigational
ATC Codes nan
Descriptionnan

Categories: Organophosphonates Organophosphorus Compounds
Cross-references: BindingDB: 25308 CHEMBL319144 ChemSpider: 115805 PDB: M0N Wikipedia: Minodronic_acid ZINC: ZINC000003803518
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
P14324 FDPS Homo sapiens Human PF00348 8.5 IC50 ChEMBL;BindingDB
O95749 GGPS1 Homo sapiens Human PF00348 6.2 IC50 ChEMBL;BindingDB
Q12051 BTS1 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) Pathogen PF00348 6.7 IC50 ChEMBL;BindingDB
DrugBank Target Actions (2)
Target Gene Target Name Action Type
O95749 GGPS1 Geranylgeranyl pyrophosphate synthase inhibitor targets
P14324 FDPS Farnesyl pyrophosphate synthase inhibitor targets