Molecule Details
| InChIKey | VLSMHEGGTFMBBZ-OOZYFLPDSA-N |
|---|---|
| Compound Name | alpha-Kainic acid |
| Canonical SMILES | C=C(C)[C@H]1CN[C@H](C(=O)O)[C@H]1CC(=O)O |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.44 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB21189 |
|---|---|
| Drug Name | Kainic acid |
| CAS Number | 487-79-6 |
| Groups | experimental |
| ATC Codes | nan |
| Description | Kainic acid is a small molecule drug. Kainic acid has a monoisotopic molecular weight of 213.1 Da. |
Categories: Anthelmintics Anti-Infective Agents Antinematodal Agents Antiparasitic Agents Excitatory Amino Acid Agents Excitatory Amino Acid Agonists Kainic Acid, antagonists & inhibitors Neurotransmitter Agents Pyrrolidines
Cross-references: BindingDB: 50002369 ChEBI: 31746 CHEMBL275040 C12819 PDB: KAI ZINC: ZINC000003995575
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q13003 | GRIK3 | Homo sapiens | Human | PF01094 PF00060 PF10613 | 8.0 | Ki | ChEMBL;BindingDB |
| Q16099 | GRIK4 | Homo sapiens | Human | PF01094 PF00060 PF10613 | 7.9 | IC50 | ChEMBL;BindingDB |
| Q13002 | GRIK2 | Homo sapiens | Human | PF01094 PF00060 PF10613 | 7.5 | Ki | ChEMBL;BindingDB |
| Q16478 | GRIK5 | Homo sapiens | Human | PF01094 PF00060 PF10613 | 7.1 | Ki | ChEMBL;BindingDB |
| P39086 | GRIK1 | Homo sapiens | Human | PF01094 PF00060 PF10613 | 6.8 | Ki | ChEMBL;BindingDB |