Molecule Details
| InChIKey | VLPRXFLUVHYBBT-VAWYXSNFSA-N |
|---|---|
| Compound Name | 6-Chloro-3-((4-methylpiperazin-1-yl)methylene)-2,3-dihydropyrrolo[1,2-a]quinazolin-5(1H)-one |
| Canonical SMILES | CN1CCN(/C=C2\CCn3c2nc(=O)c2c(Cl)cccc23)CC1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.62 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q86U86 | PBRM1 | Homo sapiens | Human | PF01426 PF00439 PF00505 | 6.9 | Kd | ChEMBL;BindingDB |
| P51531 | SMARCA2 | Homo sapiens | Human | PF07533 PF00439 PF00271 PF07529 PF08880 PF14619 PF00176 | 6.6 | Kd | ChEMBL;BindingDB |
| P51532 | SMARCA4 | Homo sapiens | Human | PF07533 PF00439 PF00271 PF07529 PF08880 PF14619 PF00176 | 6.4 | Kd | ChEMBL;BindingDB |