Molecule Details
| InChIKey | VKRJGZNMDIROFE-UHFFFAOYSA-N |
|---|---|
| Compound Name | 5-chloro-2,4-dihydroxy-N-[4-[(4-methoxyphenyl)methyl-methylcarbamoyl]phenyl]-N-[(3-methyl-1,2-oxazol-5-yl)methyl]benzamide |
| Canonical SMILES | COc1ccc(CN(C)C(=O)c2ccc(N(Cc3cc(C)no3)C(=O)c3cc(Cl)c(O)cc3O)cc2)cc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.12 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q15118 | PDK1 | Homo sapiens | Human | PF10436 PF02518 | 6.5 | IC50 | ChEMBL |
| Q15119 | PDK2 | Homo sapiens | Human | PF10436 PF02518 | 6.0 | IC50 | ChEMBL |
| Q15120 | PDK3 | Homo sapiens | Human | PF10436 PF02518 | 6.0 | IC50 | ChEMBL |
| Q16654 | PDK4 | Homo sapiens | Human | PF10436 PF02518 | 6.0 | IC50 | ChEMBL |