Molecule Details
InChIKeyVKQPTVJDZIILPG-UHFFFAOYSA-N
Compound Name4-(4-((5-Hydroxy-2-methylphenyl)amino)quinolin-7-yl)-1,3-thiazole-2-carbaldehyde
Canonical SMILESCc1ccc(O)cc1Nc1ccnc2cc(-c3csc(C=O)n3)ccc12
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Cross-Family
Avg pChEMBL7.15
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB07832
Drug Name4-{4-[(5-hydroxy-2-methylphenyl)amino]quinolin-7-yl}-1,3-thiazole-2-carbaldehyde
CAS Numbernan
Groups experimental
ATC Codes nan
Descriptionnan

Cross-references: BindingDB: 25191 CHEMBL237127 ChemSpider: 22377262 PDB: GK1 PubChem:23644582 PubChem:99444303 ZINC: ZINC000016052770
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
P07949 RET Homo sapiens Human PF00028 PF07714 PF17756 PF17812 PF17813 PF22540 7.6 IC50 ChEMBL;BindingDB
P06239 LCK Homo sapiens Human PF07714 PF00017 PF00018 7.5 IC50 ChEMBL
Q16539 MAPK14 Homo sapiens Human PF00069 6.4 Ki ChEMBL;BindingDB
DrugBank Target Actions (1)
Target Gene Target Name Action Type
Q16539 MAPK14 Mitogen-activated protein kinase 14 binder targets