Molecule Details
| InChIKey | VJKJKZOWXJKSSK-UHFFFAOYSA-N |
|---|---|
| Compound Name | 1-(6,7-Difluoroquinolin-4-yl)-3-[6-(trifluoromethyl)-2-pyridinyl]urea |
| Canonical SMILES | O=C(Nc1cccc(C(F)(F)F)n1)Nc1ccnc2cc(F)c(F)cc12 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.0 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P49841 | GSK3B | Homo sapiens | Human | PF00069 | 7.6 | Ki | ChEMBL |
| P49840 | GSK3A | Homo sapiens | Human | PF00069 | 7.4 | Ki | ChEMBL |
| P49336 | CDK8 | Homo sapiens | Human | PF00069 | 7.0 | Ki | ChEMBL |
| P07949 | RET | Homo sapiens | Human | PF00028 PF07714 PF17756 PF17812 PF17813 PF22540 | 6.0 | Ki | ChEMBL |