Molecule Details
| InChIKey | VJGGHXVGBSZVMZ-QIZQQNKQSA-N |
|---|---|
| Compound Name | Cloprostenol |
| Canonical SMILES | O=C(O)CCC/C=C\C[C@@H]1[C@@H](/C=C/[C@@H](O)COc2cccc(Cl)c2)[C@H](O)C[C@@H]1O |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.44 |
| Source | BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB11507 |
|---|---|
| Drug Name | Cloprostenol |
| CAS Number | 54276-21-0 |
| Groups | experimental vet_approved |
| ATC Codes | nan |
| Description | nan |
Categories: Abortifacient Agents Adrenal Cortex Hormones Autacoids Biological Factors Contraceptive Agents, Hormonal Eicosanoids Fatty Acids Fatty Acids, Unsaturated Hormonal Contraceptives for Systemic Use Inflammation Mediators Lipids Luteolytic Agents Prostaglandins Prostaglandins F, Synthetic Prostaglandins, Synthetic Reproductive Control Agents
Cross-references: BindingDB: 50085910 CHEMBL37853 ChemSpider: 4470590 Drugs Product Database (DPD): 249 PDB: A1D5A RxCUI: 2606 Wikipedia: Cloprostenol ZINC: ZINC000004536236
Target Activities (3)
DrugBank Target Actions (5)
| Target | Gene | Target Name | Action | Type |
|---|---|---|---|---|
| P21731 | TBXA2R | Thromboxane A2 receptor | agonist | targets |
| P34995 | PTGER1 | Prostaglandin E2 receptor EP1 subtype | agonist | targets |
| P43088 | PTGFR | Prostaglandin F2-alpha receptor | agonist | targets |
| P43115 | PTGER3 | Prostaglandin E2 receptor EP3 subtype | agonist | targets |
| Q13258 | PTGDR | Prostaglandin D2 receptor | agonist | targets |